CD25+CD8+, CLA+CD4+, CD11a+ CD4+ and CD11a+ CD8+ T Cell Counts Are Elevated in the Blood of Brazilian Patients
نویسندگان
چکیده
منابع مشابه
CD25(+)CD8(+), CLA(+)CD4(+), CD11a(+) CD4(+), and CD11a(+) CD8(+) T cell counts are elevated in the blood of Brazilian patients with chronic plaque psoriasis.
Psoriasis is a recurrent, chronic inflammatory disorder that mainly affects the skin and joints1. In view of the scarcity of studies on peripheral lymphocyte subpopulations in Brazilian psoriasis patients, we performed cytofluorometric analysis of peripheral blood mononuclear cells (PBMC) in psoriatic patients and healthy controls in order to characterize the lymphocyte subpopulations and certa...
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An important aspect of peripheral T cell development is the differentiation from naive into memory cells. To distinguish naive from memory cells, CD45RA and CD11a are commonly used: CD45RA+ or CD11a(dim) T cells are regarded as naive, while CD45RA- or CD11a(bright) T cells are thought to be of memory type. There is, however, a CD8+ T cell subset which is CD45RA+ and at the same time CD11a(brigh...
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ژورنال
عنوان ژورنال: Actas Dermo-Sifiliográficas (English Edition)
سال: 2011
ISSN: 1578-2190
DOI: 10.1016/s1578-2190(11)70826-5